Combined analysis of ploidy and cell kinetics on fine-needle aspirates from breast tumors
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چکیده
منابع مشابه
Ultrastructural analysis of fine needle aspirates from benign breast lesions.
Thirty six fine needle aspirates from various types of benign breast lesions were examined by electron microscopy and correlated with their cytological appearances. In all cases the parenchyma consisted of clumps of cohesive cells with the ultrastructural features of epithelial cells. In many cases, particularly from fibroadenomas, the parenchyma consisted of single layers of polarised epitheli...
متن کاملComputerized Diagnosis of Breast Fine-Needle Aspirates
The goal of this work is to determine the accuracy of computer-based image analysis in diagnosing breast fine-needle aspirates (FNA). On 192 FNAs, the computerbased diagnostic accuracy was 97.9%. This is consistent with the 97.5% accuracy projected by machine learning methods during the initial training in 1994 with 569 FNAs. One of the attributes of this system is the rendering of a value that...
متن کاملEnzyme immunoassay of estrogen receptors in fine needle aspirates of breast tumors.
Enzyme immunoassay of estrogen receptors (ER-EIA) was compared to radioligand assay (ER-RLA) in fine needle aspirates of breast tumors. Fine needle aspiration is a relatively atraumatic means of harvesting malignant cells from breast tumors. Fine needle aspiration provides a homogeneous suspension (about 90% malignant cells) with a sufficient amount of cellular material (10 to 50 micrograms DNA...
متن کاملAtypia in fine needle aspirates of breast lesions.
BACKGROUND The atypical category is controversial in fine needle aspiration cytology (FNAC) of the breast; most are benign, but a significant number are malignant. To date, no morphological criterion has been found to be consistent in predicting malignancy. AIMS To evaluate specific cytological parameters and assess their usefulness in predicting histological outcome in a cohort of atypical b...
متن کاملPropagation of genetically altered tumor cells derived from fine-needle aspirates of primary breast carcinoma.
Because primary breast tumors are diagnosed earlier in the clinic, procurement of sufficient amounts of tumor tissue for in-depth biological characterization is becoming increasingly difficult. We demonstrate here that relatively small numbers of tumor cells within samples of fine-needle aspirates (FNA) can be propagated in culture. Of 25 cases attempted, 12 were passageable, resulting in up to...
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ژورنال
عنوان ژورنال: Cancer
سال: 1993
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19930415)71:8<2522::aid-cncr2820710815>3.0.co;2-7